The Callisto Protocol is a third-person survival horror game set in a maximum-security prison on Jupiter's moon Callisto, where inmates are transforming into monstrous Biophage creatures. Created by the co-creator of Dead Space, it features a melee-focused combat system built around dodge timing and counter-attacks, complemented by the GRP gravity tool for environmental kills. The game emphasizes resource scarcity, atmospheric tension, and brutal close-quarters encounters in claustrophobic prison corridors. Post-launch updates added a New Game+ mode and additional difficulty options.
Resource management and crafting determine how quickly your power scales. This guide covers what to prioritize, where to farm, and how to avoid wasting resources on the wrong upgrades.
Crafting Priority List
The order you should invest resources:
| Priority | Target | Why |
|---|---|---|
| 1 | Primary equipment | Biggest damage increase per resource spent |
| 2 | Core build gear | Enables your build's key synergies |
| 3 | Defensive upgrades | Survivability for boss fights |
| 4 | Secondary equipment | Situational options for specific content |
| 5 | Consumables | Temporary boosts for hard content |
Resource Farming by Area
Black Iron Prison
Key resources: GRP unlock, Stun Baton, basic weapons, combat tutorials, first Reforge station Farming efficiency: Low value per run, but safe and consistent
Focus on gathering materials for Hand Cannon (Pistol) upgrades here. See our maps guide for detailed area layouts.
Below
Key resources: Skunk Gun, Stun Baton upgrades, underground-exclusive encounters, story revelations Farming efficiency: Good early-game farming spot
Focus on gathering materials for Hand Cannon (Pistol) upgrades here. See our maps guide for detailed area layouts.
Habitat Dome
Key resources: Mid-game boss fight, Assault Rifle unlock, open combat encounters, story progression Farming efficiency: Best mid-game farming, worth revisiting
Focus on gathering materials for Hand Cannon (Pistol) upgrades here. See our maps guide for detailed area layouts.
Tower
Key resources: Story climax setup, toughest standard enemies, Reforge station with final upgrades Farming efficiency: High-value materials for late-game upgrades
This is where you farm materials for Stun Baton max upgrades. See our maps guide for detailed area layouts.
Arcas Station
Key resources: Final boss encounters, story conclusion, endgame rewards, New Game+ unlock Farming efficiency: Best resources in the game, requires strong build
This is where you farm materials for Stun Baton max upgrades. See our maps guide for detailed area layouts.
Upgrade Path
Early Game (Black Iron Prison — Below)
- Upgrade your starting equipment to functional level
- Craft basic defensive gear
- Save specialty materials — you'll need them later
- Focus on Hand Cannon (Pistol) once accessible
Mid Game (Habitat Dome)
- Push Hand Cannon (Pistol) to mid-level upgrades
- Start collecting materials for Stun Baton
- Craft situational consumables for boss fights
- Upgrade build-specific gear pieces
Late Game (Tower — Arcas Station)
- Max out Stun Baton — this is your top priority
- Complete your build's core gear set
- Craft endgame consumables
- Optional: upgrade secondary equipment for variety
Crafting Mistakes to Avoid
- Spreading upgrades across multiple equipment — Focus one weapon to max before diversifying.
- Hoarding materials — Use them. The game provides enough if you farm efficiently.
- Upgrading the wrong gear — Check our builds guide before investing.
- Ignoring Habitat Dome farming — This area has the best resource-to-time ratio in mid-game.
- Crafting consumables too early — Save specialty materials for late-game recipes.
Resource Efficiency Tips
- Alternate dodge directions (left, right, left) to avoid all combo attacks. Dodging the same direction twice in a row gets hit by the follow-up swing.
- Farm Habitat Dome during mid-game for the best return on time
- Check the walkthrough to know when each resource becomes available
- Match your farming route to your build — some classes farm faster in certain areas
More The Callisto Protocol Guides
- The Callisto Protocol The Callisto Protocol Overview
- The Callisto Protocol Best Builds
- The Callisto Protocol Tier List
- The Callisto Protocol Walkthrough
- The Callisto Protocol Beginner's Guide
- The Callisto Protocol Tips & Tricks
- The Callisto Protocol Weapons Guide
- The Callisto Protocol Combat Guide
- The Callisto Protocol Boss Guide
- The Callisto Protocol Maps & Locations
- The Callisto Protocol Classes & Characters
Similar Games
If you enjoy The Callisto Protocol, check out these related guides:
- Phasmophobia Crafting Guide — horror game with similar mechanics
- Lethal Company Crafting Guide — horror game with similar mechanics
- Dead by Daylight Crafting Guide — horror game with similar mechanics
